ACD/ChromGenius

Key Capabilities

ACD/ChromGenius can be used to eliminate iterative experiments and instrument downtime:

• Rank a series of generic or standard chromatographic methods for a sample prior to injection, and use this information to select the best one.
• Predict chromatographic retention times.
• Build a database of retention times and structures for your own set of standard methods.
• Use an existing database of retention times and structures for pre-defined sets of generic methods (included with ACD/ChromGenius):
  • Supelco Ascentis database of structures and retention times for a set of eight LC/MS-compatible methods.
  • Thermo Electron database of structures and retention times for a set of ten LC/MS-compatible methods.
  • Specs database of retention times for thousands of structures.

Expedite high-throughput chromatography by using ACD/ChromGenius to choose the optimum separation method for your novel compounds.

For Analytical Scale Separations

• Ensure that compounds elute after the solvent front.
• Avoid carry-over between runs.
• Achieve enhanced separation quality and increased accuracy.
• Prevent co-elution of impurity and compound peaks.
• Decrease instrument downtime.

For Preparatory Scale Separations

• Choose separations according to starting materials and products.
• Enhance accuracy of results and purity of samples with higher resolution separations.
• Target conditions and elution time to increase solvent volatility and decrease solvent evaporation time.

ACD/ChromGenius Batch can perform method selections for entire sample sets!

• Input a list of samples and structures for analysis into the software.
• Return a spreadsheet containing the best generic method for each sample to import to your chromatography data system.
• View a comparison of ChromGenius and ChromGenius Batch.

For technical information about how ACD/ChromGenius works, click here.