ACD/Name

What's New

Version 4.5 to 5.0

1. Spiro compounds with polycyclic components
2. Preferred names of tautomeric forms
3. Improved stereo configuration analysis
4. Save and load user preferences

New Features in Illustrated Detail

1. Spiro compounds with polycyclic components

Spiro compounds with polycyclic components form an important subset of pharmaceutical compounds. Systematic names for polyspiro compounds with polycyclic components can now be generated for release 5.0 of ACD/Name. Previously, ACD/Name refused to name this class of structures. For example, in the following systematic name of Griseofulvin, the name of the parent spiro system is shown in bold:

2. Preferred names of tautomeric forms

ACD/Name 5.0 can now recognize possible tautomeric forms of structures and, depending on preferences, can generate names for the drawn form or for the preferred (in the nomenclature sense) form.

This option will help you avoid assignment of different names to different presentations of the same compound.

Preference: Name preferred tautomeric form
Yes	3,4-dihydro-2H-pyrrol-5-amine	3,4-dihydro-2H-pyrrol-5-amine
No	2-pyrrolidinimine

3. Improved stereo configuration analysis

Stereo isomeric forms of allenes and other polyenes can be distinguished by assignment of stereodescriptors. Additional procedures have been incorporated, to recognize previously unsupported types of stereoisomers.

For example, the name of the following chiral allene now includes stereodescriptors (shown in bold):

4. Save and load user preferences

ACD/Name allows you to change various naming options. Version 5.0 now allows you to choose the most convenient set of preferences, and save and load them. At any time you can revert to the default set of preferences, as recommended by ACD/Labs naming experts. [These are in accordance with IUPAC recommendations, except that the new functional group names are not used (e.g. thio is used instead of sulfanyl).]