| Prediction Modules available in ACD/Tox Suite | Additional Documentation | |
|---|---|---|
|
hERG Inhibition Trainable! |
Evaluate your compounds for cardiotoxicity related to drug interactions with the hERG channel | Data Sheet Model Performance |
|
P450 Inhibition Trainable! |
Predict whether your compound is likely to be an inhibitor of any of the 5 major CYP450 isoforms (3A4, 2D6, 2C9, 2C19, 1A2), and learn about probable sites of metabolism in your compounds | Model Performance |
|
Genotoxicity Trainable! |
Obtain predictions for the probability of your compounds having a positive Ames test | Data Sheet Model Performance |
| Acute Toxicity | Predict quantitative LD50 values and qualitative categories for toxic effects | Data Sheet Model Performance |
| Aquatic Toxicity | Predict LC50 values for the aquatic toxicity of your compounds. | Data Sheet Model Performance |
| Irritation | Calculate the potential of eye and skin irritation as per the Draize test | Data Sheet Model Performance |
| Endocrine System Disruption | Predict the relative binding affinity of your compounds to the Estrogen Receptor and learn about the possibility of reproductive toxicity and cancers | Data Sheet Model Performance |
| Health Effects | Predict the probable toxicity of a compound on particular organs or organ systems based on long term organ specific toxicity studies encompassing various species and routes of administration | |
| Additional Available Properties | Access a variety of fast and reliable physicochemical property predictors Learn more... | |
