Mass Spectrometry and Chromatography Software Solutions for Impurity Workflows
This presentation explores how software can improve the accuracy and efficiency of GC, LC, and MS.
Mapping the Separation of Complex Modalities Enabled by Computer Assisted Chromatography Modeling
Watch the recordings from our Virtual LC & MS Symposium featuring speakers from the pharmaceutical, medical-device, and lab-software industries discussing how they map their separation spaces, automate their data processing, build databases, and more.
How science educators can use software in remote and hybrid classrooms
Learning outside the physical science lab is challenging with classes moving online, but science educators can look to certain software to enhance students’ learning experience. Read more about how Widener University utilized ACD/Method Selection Suite to help students run virtual experiments.
Mapping the Separation Landscape in Two-Dimensional Liquid Chromatography
Customers of ACD/LC Simulator (now available as ACD/Method Selection Suite) contributed to this article on how they used the software to optimize 2D LC separations.
Introducing a New Technique to Enable Chromatographic Separation Using Computer-assisted Modelling
Imad Haidar Ahmad and colleagues at Merck present multifactorial peak crossover (MPC)—a new technique to quickly isolate peaks of interest. Using computer-assisted chromatographic modelling, the separation landscape is mapped and conditions that change peak-elution orders are found. Peaks of interest can be quickly shifted to convenient areas of the chromatogram, dramatically reducing the time spent...
Trends and Developments in Data Handling
Graham McGibbon (Director of Strategic Partnerships, ACD/Labs) participated in a panel discussion on chromatographic data handling.
Introducing Multifactorial Peak Crossover in Analytical and Preparative Chromatography via Computer-Assisted Modeling
In this article, Merck describes how they used ACD/LC Simulator to model peak crossover and improve productivity in prep LC development.
Over 40 years of method-development experience in separation science
In the interview with Christina Poggel for Wiley Analytical Science, James Hogbin talks about most important advancements in separation science, his tips and tricks for method development and the distinction between separations and analytical methods.
Generic Ion Chromatography Conductivity Detection Method for Analysis of Palladium Scavengers in New Drug Substances
In this article, the use of ACD/LC Simulator to generate 3D resolution maps with separation conditions that matched the outcome of subsequent experimental data is discussed. Method validation experiments showed excellent analytical performance in linearity, recovery, repeatability, and loq/LOD.
High-Throughput Analytical Approach Combining Automated Sample Preparation and Gas Chromatography with Universal Carbon Response
ACD/GC Simulator (a component of ACD/Method Selection Suite) was used for GC method development and separation modeling. Specifically, GC Simulator was employed to build a linear retention model for the varied experimental analytes, providing a “significant advantage for accelerating the method development process.”