The previous blog described two general approaches to analyzing data for an unknown compound: broad and focused approaches.
The table below lists the general advantages of broad and focused approaches for a structure elucidation. Depending on the data at hand, one approach can be considered the better choice. An elucidation where lots of background information is available about the unknown favors the focused approach. A broad approach is best reserved for an elucidation where little is known about the unknown. This is a common issue for the elucidation of a natural product.