Skip To Content

ACD/Labs Blog

Baljit Bains
Chromatography aims to separate an analyte mixture into sharp, symmetrical, and well-resolved peaks for quantitative and qualitative analysis. To do this, it is crucial to understand ionization and the ionic form(s) of analytes at a given pH. The use of predictive software tools allows quick selection of optimal conditions and helps build robustness into methods from the start.

Baljit Bains
The highly coveted Gaussian peak, a sharp symmetrical shape on a flat baseline, is the ideal peak shape in chromatography. Why is it so highly desired? Naturally, we tend to be drawn to the beauty of symmetry, but more importantly, good peak shape is important for better resolution (Rs) and increased accuracy in quantitation.

Charis Lam
When Widener University switched to online teaching, Chemistry Professor Scott van Bramer turned to online tools as a way to continue educating his students. ACD/Method Selection Suite provided the answer to help his students run virtual experiments, and exposed them to the type of software they will see in their eventual workplaces.

Sanji Bhal
We talk to a team at Dow AgroSciences about their decision to make changes in their laboratory to enable more efficient screening of method parameters. Using ACD/Labs’ method development software in their process enabled the team to implement a systematic approach to method development.

Gabriela Cimpan
Gabriela Cimpan reflects on her career in chromatography with a specific look at the influence of Professor Simion Gorcan of Babes-Bolyai University. As she summarizes "Chromatography, like many other things, can be loved or hated. If you happen to love it maybe, like me, you too can attribute it to an inspiring personality in your life. I was taught a long time ago: 'Put a little passion in everything you do and you will succeed'."

Sanji Bhal
In an effort to help separations scientists succeed in 2017, we decided to launch a webinar series aimed at informing the scientific community about how software can assist and improve method development strategies. Hosted by members of the ACD/Labs’ technical and scientific services team—Anne Marie Smith, Brent G. Pautler, and Karim Kassam—the webinar series consists of three 30-minute sessions on a variety of topics relating to method development.

Arvin Moser
The line shape of a peak on a chromatogram can offer some insight into the presence of a functional group. However, issues with the instrument are also known to affect the line shape for a peak. The GC/MS EI+ Total Ion Chromatogram/Current (TIC) below shows five peaks. All of the peaks with the exception of...