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ACD/Labs Blog

There are many challenges present in deciphering correlations on an HMBC experiment. Barring any data collection issues, most of the challenges will arise from signals that are overlapping, thus, adding an element of ambiguity. The 1H -13C HMBC spectrum below shows a correlation between the 13C at 71.2 ppm and the overlapping 1H signals at...

In the blog series entitled Distinguishing Impurities, several types of NMR experiments were outlined to offer some insight into what to be on the look out for. Although there is no set guideline in this process, the best advice I may offer is to keep track of all the solvents, be aware of the possibility...