Skip To Content

Logic Puzzle #46: Negative correlation on the HSQC-DEPT

A key step in being a successful elucidator is to understand the principles behind the experiment. Below is one such case.

For the following known compound, the 1H -13C HSQC-DEPT (or multiplicity-edited HSQC) spectrum (collected at 150 Hz coupling constant) below shows a negative correlation (blue) at 2.72 and 61.1 ppm with a 1H integral of 1.0. How would you assign this correlation?