How evolving analytical and automation tools are positively impacting forced degradation studies in pharmaceutical development

The goal of stress testing or forced degradation in pharmaceutical development is to comprehensively compile relevant degradation pathways, such that all degradation products are formed at detectable levels. This field has grown significantly in the past 20 years, fueled in part by the development of novel analytical and automation tools to support stress-testing procedures. This whitepaper outlines several notable examples of such solutions, including ACD/Labs Luminata™, which represents a powerful tool to provide complete analytical data management and decision support in various chemistry, manufacturing, and controls (CMC) applications, including forced degradation.