To use network pharmacology and molecular docking technology in predicting the main active ingredients and targets of Qushi Huayu Decoction treatment in Nonalcoholic Fatty Liver Disease and explore the potential mechanisms of its multi-component-multi-target-multi-pathway. Materials and Methods. The main chemical components of QHD were searched using traditional Chinese medicine system pharmacology technology platform and PubChem database. The main chemical components of the prescription were ADMET screened by the ACD/Labs software.