Showing 1-30 of 50
| ACD/Labs Releases New Software Features to Support Chemical and Pharmaceutical R&D | |
| Sep 23, 2020 | ACD/Labs |
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Press Release |
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| ACD/Labs announces its annual updates across its Spectrus and Percepta platform applications with the release of Version 2020. | |
| Read more |
| Future-Proof Your IT Infrastructure for Complete Scientific Data Management | |
| Jun 10, 2020 | ACD/Labs |
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Webinar |
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| This webinar will discuss the challenge of managing analytical data in IT systems, implications of managing data in the cloud, and industry trends in data standardization. | |
| Watch on Demand |
| Enablement Strategy for Automation in Analytical Data Management | |
| Jun 04, 2020 | ACD/Labs |
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Strategy Brief |
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| This Strategy Brief is intended to help organizational stakeholders to review analytical data accessibility needs, provide an overview of ACD/Labs software and services, and propose practical steps for realizing an automated ADMS. | |
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| How to Achieve Effective Analytical Data Management in 2020 | |
| Jan 29, 2020 | M. Riese |
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Webinar |
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| In this 40 minute webinar we will discuss ACD/Spectrus, ACD/Labs' comprehensive, multi-technique, instrument vendor-agnostic analytical data management system (ADMS). Start the new year off right by learning how to revolutionize your data management strategy with ACD/Labs! | |
| Watch on Webinar |
| ACD/Labs Releases v2019 Software Updates to its Spectrus and Percepta Platform Applications | |
| Sep 18, 2019 | ACD/Labs |
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Press Release |
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| Software enhancements offer a complete application for CMC decision support, improvements for analytical data processing and analysis, and a move to 64-bit architecture. | |
| ACD/Labs Releases v2019 Software Updates to its Spectrus and Percepta Platform Applications |
| ACD/Labs: Empowering Data-driven Decisions | |
| Jun 26, 2019 | ACD/Labs |
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Article |
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| This guide to informatics and data integrity published by the European Pharmaceutical Review highlights ACD/Labs software solutions including our Spectrus and Percepta platforms, and new solutions Luminata and Katalysts D2D. | |
| Read more |
| ACD/Labs® Releases Updates to its Foundational Spectrus® and Percepta® Platforms | |
| Oct 24, 2018 | ACD/Labs |
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Press Release |
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| The release of ACD/Labs' v2018.1 software includes major enhancements to its analytical knowledge management solutions for pharmaceutical development, MS and NMR dereplication workflows, and chromatography offerings. | |
| ACD/Labs® Releases Updates to its Foundational Spectrus® and Percepta® Platforms |
| Targeted Dereplication of Microbial Natural Products by High-Resolution MS and Predicted LC Retention Time | |
| Jul 21, 2018 | M. McKee, ACD/Labs |
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Poster |
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| A new strategy for identification of known compounds in Streptomyces was developed via combined screening of two natural product databases. StrepDB contains LCMS data for 5555 natural products, and was screened using a high-throughput processing algorithm that rapidly identifies known compounds using HRMS data and predicted LC retention times. MbcDB contains structures and analytical data for 665 natural products and was generated using Spectrus DB. StrepDB was used to screen a mutant Streptomyces albus extract, which led to the identification of two new compounds, legonmaleimides A and B. Their proposed structures were then confirmed by computer-assisted structure elucidation methods using ACD/Structure Elucidator Suite. This strategy suggests an extract dereplication pipeline approach that can be applied to natural product discovery. | |
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| The State of Scientific Analytical Data Management | |
| Jun 15, 2018 | ACD/Labs |
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eBook |
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| In an era where analytical instruments are becoming more and more sophisticated, and the amount and types of data collected are increasing exponentially, we partnered with Cell Associates and C&EN to conduct a formal industry survey on Analytical Data Management. Read this eBook to discover our key findings on how laboratories manage all the analytical data they produce. | |
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| Discovering the Fourth Paradigm in Data Standardization | |
| Apr 01, 2018 | G.A. McGibbon and A. Anderson |
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Article |
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| Graham McGibbon and Andrew Anderson of ACD/Labs write about how the externalization of R&D activities and the deluge of instrumental analytical data generated on a daily basis has resulted in increasing interest in analytical data standardization. | |
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| Addressing the Unique Challenges of Analytical Data Management in the Modern R&D Environment | |
| Nov 03, 2017 | ACD/Labs |
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Poster |
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| Commonly used informatics technologies do not effectively manage the unique challenges of analytical data management. While data abstraction serves a purpose, it also has limitations since important details, knowledge, and contextual information can be lost. | |
| Download Poster |
| ACD/Labs Announces Updates to its Spectrus Informatics Platform | |
| Oct 18, 2017 | ACD/Labs |
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Press Release |
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| V2017.1 release of ACD/Spectrus software introduces an innovative solution for impurity data management and exciting developments for deconvolution and analysis of mixtures. | |
| ACD/Labs Announces Updates to its Spectrus Informatics Platform - October 2017 |
| Analysis of Mixtures by NMR Spectroscopy: Current Workflow Solutions using the ACD/Spectrus Platform | |
| Sep 18, 2017 | D. Argyropoulos, B. Pautler, S. Golotvin, S. Jahanbakht, V. Mikhalenko |
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Poster |
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| Download |
| IntelliXtract 2.0: Simplified Intelligent Component Extraction and Detection | |
| Jun 08, 2017 | A.M. Smith, R. Lee, V. Lashin, A. Paramonov |
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Poster |
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The analysis of real-world samples is becoming increasingly complex and time-consuming. Scientists frequently use techniques, such as chromatography to aid in the separation of differing compounds and components. Liquid Chromatography-Mass Spectrometry (LC-MS) has been the primary platform for determination of differing components when chromatographic co-elution was inevitable. Software can aid in simplifying the data-mining process and increase the speed of discovery. An earlier algorithm for component detection, named IntelliXtract (IX), implemented a method of extracted ion chromatograms (XICs) that were automatically generated and assigned a component number, thereby simplifying the analysis process, but was computationally demanding. Here we describe a simplified and more optimized algorithm based on the use of ion threads vs. XICs. |
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| View Poster |
| A new biotransformation prediction engine integrated into a metabolite identification solution | |
| Jun 07, 2017 | Richard Lee, Rytis Kubilius, Vitaly Lashin, Alexandr Sakharov |
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Poster |
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| In the analysis of xenobiotic metabolism, there have been a number of advancements in the hardware used, as well as the software that processes LC-MS data for metabolite identification. However, bottlenecks remain in the workflow, and especially in the structure elucidation phase. Here we present a new prediction algorithm that determines the likelihood of biotransformation reactions, and subsequent metabolite identification, within an automated processing routine. | |
| View Poster |
| A new method for analyzing MSE/All Ions Fragmentation in Xenobiotic metabolism studies | |
| Jun 07, 2017 | Richard Lee, Vitaly Lashin, Andrey Paramonov, Alexandr Sakharov |
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Poster |
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| As an alternative to traditional Data Dependent Acquisition (DDA), the use of MSE/All Ions Fragmentation (AIF) has become common in metabolite identification workflows for the analysis of metabolic hot spots. Although, MSE/AlF has its advantages, the non-specific fragmentation of precursor ions possess a challenge for structure elucidation due to the confounding fragment ions from other species. Here we present a solution for analysis of MSE/AlF in metID studies. | |
| View Poster |
| Addressing the Unique Challenges of Analytical Data Management in the Modern R&D Environment | |
| May 24, 2017 | G.A. McGibbon, S.K. Bhal |
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Poster |
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| Effective analytical data management brings unique challenges that are not easily addressed by the majority of scientific informatics technologies commonly in use in R&D (ELN, LIMS, CDS, Raw data archives, etc.). The large variety of analytical data generated through a product's R&D lifecycle is driving a growing acceptance of the need for the homogenization of spectroscopic and chromatographic data. Furthermore, while data abstraction—a result of digitization of analytical data to text, numbers, and images—serves a purpose, it also brings limitations since important details, knowledge, and contextual information can be lost. | |
| View Poster |
| Looking Beyond Analytical Data Standardization - the Fourth Paradigm | |
| May 15, 2017 | A. Anderson, G. McGibbon, A. Paramonov, S. Bhal |
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Whitepaper |
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| In this white paper we provide commentary on factors that impact analytical data standardization and a vision of the considerations and requirements that such an undertaking should include. | |
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| Let your Data live On: the ACD/Labs Approach to Laboratory Informatics | |
| Feb 20, 2017 | Maria Varlan |
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Presentation |
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| Download |
| Impurity Lifecycle Management: Visualizing a Vast Array of NMR and Other Analytical Data | |
| Feb 20, 2017 | S. Coombes, J. Nightengale, A. Micottis, A. van Wyk, P. Russell, D. Argryopoulos, S. Albrecht |
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Poster |
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| Drug Development is a process that takes years and results in huge amounts of information being generated. Thousands of individual experiments and tests, and hundreds of reports produce terabytes of data. A concise summary of the process is the Marketing Application report but this typically runs into hundreds of pages to describe the impurity control strategy. | |
| Download |
| Boehringer Ingelheim Selects ACD/Labs for International Deployment | |
| Nov 30, 2016 | ACD/Labs |
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Press Release |
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| Implementing software on the ACD/Spectrus Platform simplifies the IT landscape and provides essential analytical data handling tools for leading pharmaceutical company. | |
| Boehringer Ingelheim Selects ACD/Labs for International Deployment |
| Replacing Pen and Paper in the Laboratory | |
| Nov 10, 2016 | J. Bienert (Max-Planck-Institute) |
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AppNote |
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| The Max-Planck Institute for Biophysical Chemistry have replaced their paper lab journals with the ACD/Spectrus Platform to access all of their data via an interface that they created and optimized in house. | |
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| Facing a formidable challenge | |
| Oct 31, 2016 | S. Ktori (Scientific Computing World) |
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Article Third-Party Reference |
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| Andrew Anderson and Graham A. McGibbon discuss ACD/Labs' partnership with the Allotrope Foundation. | |
| Read Article |
| Schwabe Pharmaceuticals Selects ACD/Labs for Analytical Data Handling and Knowledge Management | |
| Oct 19, 2016 | ACD/Labs |
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Press Release |
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| Deployment of ACD/Spectrus software provides an efficient, common software environment for data processing and analysis, helping scientists leverage analytical knowledge. | |
| Schwabe Pharmaceuticals Selects ACD/Labs for Analytical Data Handling and Knowledge Management |
| ACD/Labs Announces Updates to its Informatics Software | |
| Oct 12, 2016 | ACD/Labs |
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Press Release |
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| V2016.1 of ACD/Spectrus and Percepta delivers improved knowledge sharing and data-driven decision support for R&D organizations. | |
| ACD/Labs Announces Release of Updated Software |
| 'I think I have had this feeling of deja-vu before'...Using a DMPK database | |
| Sep 27, 2016 | S. Thomas (GSK) |
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Presentation |
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| Download |
| Pilot Study to Automate Forced Degradation Workflows | |
| Sep 27, 2016 | D. Benstead (AstraZeneca) |
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Presentation |
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| Download |
| Impurity Lifecycle Management—Visualising a Vast Array of Analytical Data | |
| Sep 27, 2016 | S. Coombes (AstraZeneca) |
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Presentation |
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| Download |
| Working with CROs in Metabolite Identification | |
| Sep 27, 2016 | L. Mason (Syngenta) and R. Mumford (Smithers Viscient) |
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Presentation |
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| Download |