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Principles of Organic Nomenclature

R-1.2.1 Substitutive operation

The substitutive operation involves the exchange of one or more hydrogen atoms for another atom or group. This process is expressed by a prefix or suffix denoting the atom or group being introduced (see R-3.2 and R-4 for lists of prefixes and suffixes).

Examples to R-1.2.1


(substitutive prefix = chloro)


(substitutive suffix = thiol)

R-1.2.2 Replacement operation
R-1.2.3 Additive operation
R-1.2.4 Conjunctive operation
R-1.2.5 Subtractive operation
R-1.2.6 Ring formation or cleavage
R-1.2.7 Rearrangement
R-1.2.8 Multiplicative operation

This HTML reproduction is as close as possible to the published version [see IUPAC, Commission on Nomenclature of Organic Chemistry. A Guide to IUPAC Nomenclature of Organic Compounds (Recommendations 1993), 1993, Blackwell Scientific publications, Copyright 1993 IUPAC]. If you need to cite these rules please quote this reference as their source.

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