Don't have a referenced LC column on hand? ACD/Column Selector can help you to find the most equivalent ones. Need a column that is different from yours in a particular way? Column Selector can help with this as well. With Column Selector, you can take the guesswork out of column selection.
ACD/Column Selector is a tool, developed in collaboration with Mel Euerby (HiChrom and University of Strathclyde) and Patrik Petersson (Novo Nordisk and Uppsala University). Available through ACD/ChemSketch, Column Selector allows you to search a knowledgebase of the most commonly used reversed phase materials to locate columns which have different selectivity for method development, or columns with similar selectivity for backup. The Column Selector database contains information for 319 characterized columns, along with results for 5742 systematic experiments.
Please note: To use Column Selector, you need to download and install ACD/ChemSketch Freeware.
In order to extend the capability of Column Selector still further, chromatographers from around the world are invited to characterize materials that are currently not included, so that these columns can be added to future releases of the application.
One chromatographic column can be characterized in just one day. Detailed instructions for performing the experiments, with the readily-available samples, are available for download. When replying, users are invited to use the Excel calculation spreadsheet included with the package, and e-mail the results to columnselector@acdlabs.com.
1 Euerby, MR; Petersson, P. "Chromatographic classification and comparison of commercially available reversed-phase liquid chromatographic columns using principal component analysis." J. Chromatogr. A, 994: 13–36, 2003.
