Mantidisflavin A
In this compound the riboflavin skeleton was supplemented by the formation of two additional fused heterocycles through a novel C−C bond and an oxygen bridge on the riboflavin backbone. The structure of mantidisflavin A (molecular formula C17H19N4O6) was elucidated using 1D and 2D NMR spectra in combination with HR-ESI-MS and IR.
DMTA Innovation at Takeda—Digitalized, AI-Augmented, Autonomous
Discover how Takeda is accelerating chemical process development with AI-enabled high-throughput experimentation (HTE), automation, and integrated hardware/software. Hear real-world success stories of shortening project times from weeks to days; and how technology partnerships are accelerating autonomous, AI-guided workflows in pharmaceutical R&D.
June 24th @ 10:00 EST, Register Now
Navigating Drug Design in ‘Beyond the Rule of 5’ Landscape
As drug discovery expands beyond traditional boundaries, complex small molecules like PROTACs challenge old rules. Discover how ACD/Labs’ predictive platforms help scientists design bioavailable, scalable drugs in the evolving ‘bRo5’ space with precision and confidence.
Streamline Stability Decisions in Pharmaceutical Development
J. DiMartino, ACD/LabsThis webinar highlights how Luminata® simplifies pharmaceutical stability decisions by integrating forced degradation and APS data. Learn to visualize analytical data, map degradant pathways, and model stability trends for faster, more informed decision-making.
Augmentation of ACD/Labs pKa® Prediction Algorithm with Proprietary High-Quality Data
Discover how ACD/Labs teamed up with AstraZeneca to enhance pKa predictions. By integrating proprietary experimental data and refining prediction algorithms, we unlocked new insights and accuracy gains – paving the way for more confident decision-making in modern drug discovery.