Comparison of ACD/LogP Freeware & Commercial ACD/LogP DB

Commercial	Freeware
Obtain calculated logP values for up to 999 structures at a time Check and choose tautomeric forms Added features of ACD/LogP DB Calculate an array of liquid properties (including PSA, #FRB, BCF, K_oc, and Rule-of-5 properties) View the calculation protocol for each individual prediction Search the internal database for literature references by substructure, IUPAC name, logP value, etc. Build your own databases of logP values Import and process SDfiles Access to scripting tools for calculation of related parameters Improve accuracy of prediction with your own experimental data using our training tools—System Training and Accuracy Extender	Obtain calculated logP values for individual structures in ChemSketch using the version 10 model Check and choose tautomeric forms

Commercial

Freeware

Obtain calculated logP values for up to 999 structures at a time
Check and choose tautomeric forms

Added features of ACD/LogP DB

Calculate an array of liquid properties (including PSA, #FRB, BCF, K_oc, and Rule-of-5 properties)
View the calculation protocol for each individual prediction
Search the internal database for literature references by substructure, IUPAC name, logP value, etc.
Build your own databases of logP values
Import and process SDfiles
Access to scripting tools for calculation of related parameters
Improve accuracy of prediction with your own experimental data using our training tools—System Training and Accuracy Extender

Obtain calculated logP values for individual structures in ChemSketch using the version 10 model
Check and choose tautomeric forms

Note: If you are working with ionizable compounds, remember that logP is only relevant for the neutral substance. To take ionization into account you must use the pH-dependant hydrophobicity descriptor, logD