‘I think I have had this feeling of deja-vu before’…Using a DMPK database
As presented by Steve Thomas at ACD/Labs Cambridge Symposium 2016.
Database extraction of metabolite information of drug candidates: Analysis of 27 AstraZeneca compounds with human ADME data
As part of the drug discovery and development process, it is important to understand the human metabolism of a candidate drug prior to clinical studies. Pre-clinical in vitro and in vivo experiments across species are conducted to build knowledge concerning human circulating metabolites in preparation for clinical studies and therefore, the quality of these experiments...