Skip To Content

Logic Puzzle #20: Which CH2 will split? … Solution

September 20, 2011

Diastereotopic protons that are also anisochronous exhibit different chemical shifts. As a general rule, the proximity of a chiral centre will influence the likelihood of diastereotopic proton signals being anisochronous.

For the structure below, the CH2 labeled A is most likely to be anisochronous due to the adjacent chiral carbon.

IUPAC: methyl 7-hydroxy-3,5-dioxo-7-phenylheptanoate


A thanks goes to Carlos for submitting a comment.

2 Replies to “Logic Puzzle #20: Which CH2 will split? … Solution”


Your email address will not be published.