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ACD/Labs Blog

Depending on the experimental conditions, signals from exchangeable protons such as NH and OH can be present on a 1H NMR spectrum. A key to interpreting a 1H NMR is distinguishing between CHn protons (where n = 1, 2 or 3) and exchangeable protons. Acquiring an 1H-13C 2D NMR experiment can assist in this process,...

I got some great comments from Tony and Gary on the “Dealing with a Mixture…” post that I decided to do a follow-up post. http://acdlabs.typepad.com/elucidation/2008/02/dealing-with-a.html In my lab days, I would routinely workup a newly acquired 1H NMR for an unknown sample prior to acquiring a 2D NMR dataset. One of my goals was to examine...