November 9, 2012
by Arvin Moser, Team Manager, Application Scientists, ACD/Labs
Depending on the mixing time, HSQC-TOCSY experiments generally offer information on both short-range and long-range coupled nuclei. The issue arises in sorting out the HSQC correlations from the TOCSY ones.
For an unknown compound, a 1H -13C HSQC-TOCSY spectrum was collected. The expanded region of the spectrum below shows several correlations. How many HSQC-related correlations are there? How many TOCSY-related correlations are evident?
Thank you Gary M. for supplying the data.