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ACD/Labs Blog

Mikhail Elyashberg
Hypocrolide A A particular type of sesquiterpenoids are botryanes. The have the same basic skeleton of a bivyvliv nonisoprenoid system. They have only been found in a few fungal species, including the pathogen Botrytis cinereal, a necrotrophic plant. Since they are sesquiterpene metabolites they expected, and they do show, various biological activity. Yuan at al...

Dimitris Argyropoulos
Benchtop NMR instruments are becoming an indispensable addition to the analytical laboratory for their ability to make NMR spectroscopy more accessible to chemists. Here we discuss the newer applications of benchtop NMR including material testing, flow chemistry and use in teaching.

Mikhail Elyashberg
Leonuketal Leonurus Japonicus is a plant that is used in common traditional Chinese medicine. In fact, the aerial parts of it are in the Chinese Pharmacopoeia. Many diterpene metabolites have been discovered on plants of the same genus, with the common characteristics of the furanolabdane class. This class has been found to have interesting bioactivities...

Mikhail Elyashberg
Lucidumone Meroterpenoids are natural products containing a terpenoid and a non-terpenoid part. There have been many classes of such compounds isolated and characterized so far, from various natural sources, several of which have been found to have a wide range of biological activities. Meroterpenoids from various fungi usually show considerable biological activity and for this...

Mikhail Elyashberg
E. Ioannou et al have developed an integrated metabolomic platform for the identification of known compounds and detection of new metabolites at the early stages of phytochemical analysis. Vagiallene was isolated through a series of chromatographic separations, molecular formula C15H15Br2O5.

Mikhail Elyashberg
Spirobisnaphthalenes are a relatively new and rare family of secondary metabolites. Their core structure usually consists of two bicyclo[4.4.0]decane units, connected with one another through at least one spiro center. The reported compound is a novel symmetric spirobisnaphthalene with a unique structural feature. Spiroaxillarone A, molecular formula C19H12O6.

Sanji Bhal
There just doesn't seem to be enough hours in the day to get everything done. There are ways to gain time and be able to do more but they can be difficult to identify because until we’re exposed to them we carry on as we always have. If you are still doing any of the things discussed here, then there are ways you can gain hours in your day and even do your job better than you are right now!

Yalda Liaghati
There are numerous ways that the 3D structure of a molecule can be elucidated, including the use of our own ACD/Structure Elucidator software. I had the chance to sit down with Dimitris Argyropoulos, our NMR Business Manager, after SMASH 2019 and discuss 3D structure elucidation and the technology involved in its current and future use.

Yalda Liaghati
Reliable structure verification of candidate molecules is at the very core of any successful chemical discovery or development program. NMR provides unprecedented levels of information for unraveling the actual structure of compounds, and is an essential tool for chemists to confirm that they made what they intended to make. Read on to learn about ACD/Labs' efforts in the area of structure verification.