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ACD/Labs Blog

Chromatography is a powerful a flexible technique at all stages of chemistry research. Whether you are a graduate student attempting purify a compound or a pharmaceutical company attempting to test product quality, an effective chromatographic method is critical. But how do you develop these methods? Optimizing chromatography techniques is notoriously time consuming and frustrating work....

What do a racecar and an LC/MS system have in common? They’re both sophisticated machines whose performance must be measured by applicable standards. Scientists have long recognized the importance of standards, but with improvements in technology, the way we set them has changed. How can we use standardization to better communicate cutting-edge science? How can...

In LC Method Development I to III, we covered the key points of method development: figuring out the project purpose, choosing parameters for screening, and optimizing. How do you assemble all these components into one workflow and manage them efficiently? This webinar puts it all together by showing you how to manage your projects from...

Optimized LC methods give the results you need to satisfy customers, synthetic chemists, QC teams, and other end users. Compared to trial and error, a proper optimization process saves time and resources. And with optimization software, you can get even more efficient. In this webinar, we’ll cover the principles you need to know for method...

Method development is a journey into the unknown. The destination may be clear enough, if you’ve defined your project goals. But unforeseen challenges lurk to trip up the unwary chromatographer. Before you know it, your two-week project has become a six-week odyssey, with events like: “Where did my compound go?” “Why are my peaks lopsided?”...

Chromatographers often speak of developing methods and separating compounds—two related but not identical ideas. Besides separating analytes, a high-quality method must meet many other criteria, including robustness, linearity, and limits of detection. To specify these factors, scientists must start with defined goals. What do you need the method to tell you? And how do you...

How ACD/Labs Enables More Robust, Efficient Separations With the increasingly challenging demands confronted by separation scientists on their expertise, resources, and time, traditional chromatography approaches are often lacking. Chromatographers require advanced informatics solutions that offer comprehensive coverage of all method development functions. Learn how ACD/Labs’ strategies enable compliance with Quality by Design (QbD) regulatory expectations,...