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ACD/Labs Blog

Sherry Myles
Toronto, Canada (August 18, 2011)—Hochschule Aalen, a research-centered academic institution in Germany, has acquired ACD/ChromProcessor in order to process, compare, combine, and report data produced from capillary electrophoresis of proteins from different detectors. ACD/ChromProcessor consolidates proprietary data formats from most major instrument vendors, making it easy for those working in labs with multiple systems to...

Sherry Myles
Combined proficiencies promise rapid and robust method development. Toronto, Canada (June 23, 2011)—Advanced Chemistry Development, Inc., (ACD/Labs) today announced compatibility with Waters’ ACQUITY UPLC H‑Class. ACD/AutoChrom for Empower 2 can be employed to control the solvent parameters and operation of the UPLC for subsequent data reduction and decision support. Using the UPLC H‑Class’ quaternary solvent...

Arvin Moser
TLC (Thin Layer Chromatography) offers a simple approach to identifying a solvent(s) for separating out a mixture, monitoring a reaction to completion, etc. Furthermore, the TLC plates can be stained to identify the presence or absence of various functional groups such as amines, ketones, etc. This qualitative experiment does offer various drawbacks. The process of...

Arvin Moser
The line shape of a peak on a chromatogram can offer some insight into the presence of a functional group. However, issues with the instrument are also known to affect the line shape for a peak. The GC/MS EI+ Total Ion Chromatogram/Current (TIC) below shows five peaks. All of the peaks with the exception of...

Arvin Moser
In the constant pursuit of new pharmaceutical drugs, process chemists (sometimes referred to as medicinal or synthetic chemists) must investigate all impurities detected in a new drug manufacturing process. The chemist’s procedure is simple: identify, elucidate and synthesize each and every single impurity. The chromatogram (UV detector set at 254 nm) below shows three peaks....