Chromatography Archives - Page 8 of 9

Adaptation of Retention Models to Allow Optimization of Peptide and Protein Separations

ACDLabs Aug 17, 2017

Learn about adaptation of ACD/Method Selection Suite to model protein and peptide separations via RPC & IEC gradient chromatography, with the same simulation accuracy as for small molecules.

Smarter Method Development – Webinar III: A 5 Step Strategy to Improve Complex Method Development with Software & Automation

ACDLabs Mar 8, 2017

The number of variables that you can investigate to achieve the optimal method for complex samples can be overwhelming. This final webinar in our series (Smarter Method Development) highlights how software can provide a systematic and exhaustive approach towards method development with as much or as little expert intervention as desired. We will introduce you...

How “Smart” is Your Method Development?

Sanji Bhal Jan 27, 2017

This webinar series presents how software can assist and improve method development strategies in three 30-minute sessions on a variety of topics relating to method development.

Smarter Method Development – Webinar I: 3 Simple Ways Software Can Speed Your Method Development

ACDLabs Jan 18, 2017

What is your method development strategy? This webinar is for you if you: Rely on knowledge and chemical intuition to choose a starting point Run iterative experiments to optimize methods Let us introduce you to some simple software tools that can help you speed up method development and optimization with minimal disruption to the way...

Chromatography Method Optimization (2 Parameters)

ACDLabs Jan 4, 2017

Model and Optimize a two parameters (Gradient concentration & temperature, etc.) for LC separation in less time with fewer injections. 5.0min

Chromatography Method Optimization (1 Parameter)

ACDLabs Jan 4, 2017

Model and Optimize a single parameter (pH, Gradient concentration, temperature, etc.) for LC Separation in less time with fewer injections. 4.0min

Prediction Models of Retention Indices for Increased Confidence in Structural Elucidation during Complex Matrix Analysis: Application to Gas Chromatography Coupled with High-Resolution Mass Spectrometry

ACDLabs Aug 2, 2016

This article discusses how using the mean of the LRI values predicted by RapidMiner and ACD/ChromGenius, in combination with accurate mass data, could enhance the confidence level for compound identification from the analysis of complex matrixes; the goal being to reduce the list of putative candidates to a reasonable number that can be obtained and...

Translations Between Differing Liquid Chromatography Formats: Advantages, Principles, and Possible Pitfalls

ACDLabs Aug 1, 2014

The numerous advantages of translating gradient chromatographic methods between the differing formats of liquid chromatography (LC) have been explored and discussed. The authors investigate a number of potential pitfalls that may result in poor translations, and examine the consequences.

Better, Faster Method Development at Janssen

ACDLabs Apr 7, 2014

How Software Can Aid Decision-Making in Chromatographic Method Development

ACDLabs Mar 26, 2013

Chromatographic method development continues to be one of the most challenging tasks for separations scientists today. In this article we discuss a comprehensive strategy for investigating design space and optimizing methods using ACD/AutoChrom software. A strategy that combines hardware, software, and personal and organizational knowledge is highlighted. Return on investment is also presented by scientists...

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