Skip To Content

ACD/Labs Blog

Jesse Harris
Is there anything that analytical chemists hate more than false positives and false negatives? While it is impossible to eliminate error completely, it is possible to control it. Understanding the relationship between false positives and negatives allows us to optimize our experimental design. We discuss more in this blog post.

Sanji Bhal
ACD/Labs is committed to supporting scientific experts from many of the world’s leading biopharmaceutical and chemical companies in identifying, verifying, and elucidating chemical structures. Recently, we brought together some of these experts to discuss their workflows and how they’ve improved efficiency and confidence in structure determination.

Baljit Bains
Mass spectrometry (MS) is a valuable tool that can give you vast amounts of MS data to help you identify and quantify components. MS has been used to discover, determine, and quantify sample compounds in the proteomics, metabolomics, imaging, and glycomics applications across the food, pharmaceutical, and environmental industries. Combining MS with appropriate software and computer technology allows the possibility for more extensive applications. But first, we must understand the basics.

Mikhail Elyashberg
Using the traditional method of structure elucidation based on analysis of HSQC, HMBC and COSY data, the authors deduced a large part of the molecular structure, but the lack of carbons bearing hydrogen atoms prevented them to assemble the full structure. To alleviate this problem, ACD/Structure Elucidator was utilized in Trichopsistide A, molecular formula C23H29NO5.

Arvin Moser
Due to their broad peaks and wide range of chemical shifts in 1H NMR spectra, exchangeable protons are known to pose challenges in NMR interpretation, but collecting 2D spectra and selecting proper experimental conditions can sometimes be used in our favor to learn more.

Mikhail Elyashberg
Tistechok et al. described the isolation, purification, and structure elucidation of a new naphthoquinone-based meroterpenoid, Furaquinocin L from Streptomyces sp. Je 1-369, which expands the structural diversity of the furaquinocin family of natural products.

Andrew Anderson
A new year is historically a time for reflection. In 2022, ACD/Labs has been in the scientific software industry for 28 years. In this blog post, Andrew Anderson reflects on three key topics have come up repeatedly in conversations with customers in 2022 that are notable for our work ahead.

Sanji Bhal
From new instruments and software to the rise of the digital lab, the landscape of analytical chemistry data is constantly evolving. To stay on top of trends, we launch a comprehensive survey every few years focused on analytical chemistry data and its management. Here's what we learned.

Mikhail Elyashberg
Shaker et al. recently reported the isolation of Dichocetide D from the marine fungus Dichotomomyces cejpii under oxygen stress conditions. The structure of Dichocetide D was revised by Elyashberg et al on the basis of chemical considerations and utilization of ACD/Structure Elucidator.