ACD/Labs Blog

Jin et al studied the novel analgesics used in traditional Chinese medicine and as part of this they isolated and elucidated the structure of a novel triamine monoterpene indole alkaloid, Gelstriamine A, molecular formula C₂₂H₂₇N₃O₅.

Asperspiropene A was first reported by He et al as the second derivative of a class of compounds containing a unique six-membered ring substructure. The molecular formula was determined from the HR-MS spectrum to be C₁₇H₂₆O₈.

Iridiod Glycoside Clerodendrum (Lamiaceae) is a genus composed of 580 species. It is found in tropical and subtropical regions and mainly includes small trees, shrubs, and herbs. Many members of the genus havebeen used in traditional medicine around the world. C. myricoides is a shrub with bluish flowers that has been used extensively in traditional...

Lyaline. Structure revision The original sample of lyaline was isolated from the roots of a Madagascan rubiaceous plant, Pauridiantha paucinervis in 1974. It was then reported to have a unique harman-1,4-dihydropyridine scaffold (1). That structure was determined only from EIMS and incomplete 1H NMR data, as recording 13C NMR spectra was not routinely available at that...

Davidone F Sophora davidii (Franch.) belong to the family Fabaceae and are shrubs or small trees found in China. Over the years many natural products have been isolated from them, including alkaloids, steroids, lignans, phenolic acids and, mostly, flavonoids. These have been found to have varying biological activities. The chemical investigation of S. davidii which...

Trichilianone D Trichilia species, a genus of plants from the Meliaceae family, are found in tropical forests and are used in traditional medicine. This species is poorly investigated and so a phytochemical study was published just recently [1]. This included the isolation of metabolites and the testing for antileishmanial activity. The study was focused on...

Rhodimer Atilaw et al [1] have been studying the roots of Tephrosia rhodesica, a member of the tropical and subtropical Tephrosia genus consisting of more than 400 species. A new variety of flavonoids has been found in them with promising biological activities (antiplasmodial). They isolated five new compounds including rhodimer 1. Its structure was determined...

Securamine H Bryozoans belonging to the Flustridae family have been shown to be a rich source of structurally unique secondary metabolites. Hansen et al [1] examined the organic extract of Securiflustra securifrons. This resulted in the isolation of three new halogenated, hexacyclic indole-imidazole alkaloids, including securamine H(1), together with the previously known securamines C (2)...

Isatisindigoticanine I Ban Lan Gen, Isatis tinctoria L. (synonym Isatis indigotica Fort.), of the Brassicacene family, is a biennial herbaceous plant. It is widely cultivated and distributed in China, where its roots are used in Traditional Chinese Medicine (TCM) for the treatment of many diseases. Ban Lan Gen was studied, and a series of alkaloids...