ACD/Labs Blog

E. Ioannou et al have developed an integrated metabolomic platform for the identification of known compounds and detection of new metabolites at the early stages of phytochemical analysis. Vagiallene was isolated through a series of chromatographic separations, molecular formula C₁₅H₁₅Br₂O₅.

Spirobisnaphthalenes are a relatively new and rare family of secondary metabolites. Their core structure usually consists of two bicyclo[4.4.0]decane units, connected with one another through at least one spiro center. The reported compound is a novel symmetric spirobisnaphthalene with a unique structural feature. Spiroaxillarone A, molecular formula C₁₉H₁₂O₆.

Chloraserrtone A, a new sesquiterpenoid dimer with two lindenane-type sesquiterpenoid monomers bridged by two six-membered rings, was isolated from Chloranthus serratus by Bai et al. It represents the first lindenane-type sesquiterpenoid dimer with an extremely unique skeleton, molecular formula C₃H₃₆O₉.

The Penicillium sp. KFS28 fungus was isolated from a bivalve mollusk, Meretrix Lusoria, from the Haikou Bay in China. The EtOAc extract of the fermentation broth was processed by the authors who isolated and identified four new paxilline-type indole-terpenoids. Compound 1 has the molecular formula C₂₈H₃₅NO₆.

Goudou at al described the isolation of a novel metabolite, orbicularisine, from the tropical bivalve Codakia orbicularis living in seagrass beds, molecular formula C₁₃H₁₀N₂O₅S.

Feng et al investigated the chemical constituents of N. tabacum leaves by a dereplication procedure, which resulted in the isolation of a novel compound, nicotabin A, molecular formula C₂₁H₂₈O₇.

Gao et al isolated, amongst others, Cascarinoid A, the first example of a crotofolane diterpenoid alkaloid, molecular formula C₂₈H₃₁NO₅.

Zhao and coworkers had been studying the secondary metabolites of Biscogniauxia sp. They isolated a diisoprenyl-cyclohexane-type meroterpenoid dimer with a new skeleton, Dimericbiscognienyne A (molecular formula C₃₂H₄₀O₆).

Yaouba et al reported the isolation and phytochemical investigation of the constituents of Aspilia pluriseta Schweinf and Aspilia mossambicensis. They isolated, identified and comprehensively investigated compound 1, molecular formula C₂₁H₃₀O₃.

El-Elimat et al reported five new and one known meroterpenoids, including the discovery of a novel ioxa[4.3.3]propellane metabolite neosetophomone A that incorporates a 3-methyl-2,3-dihydrofuran bridge into a 5,6 tricyclic 2-hydroxycyclopent-2-en-1-one/tetrahydropyran ring system, molecular formula C₂₄H₃₂O₅.